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GSTs have been implicated in the development of resistance toward chemotherapy agents

doi: 10.1126/scitranslmed.aaa3863

Health Risks and Side EffectsMisuse of boldenone is associated with a wide range of severe health disorders: Cardiovascular Issues: Risk of heart problems.Liver and Kidney Damage: Potential for hepatic (liver) and renal (kidney) impairment.Reproductive Issues: In males, it can cause decreased natural testosterone production, reduced testes size, lower sperm count, and decreased sperm mobility.Psychological Effects: Can lead to behavioral and neurochemical alterations, including anxiety, aggression, and mood disorders.Carcinogen Classification: It is classified as a probable human carcinogen by the International Agency for Research on Cancer

This helps calm their nervous system

Increasing one pathway while disrupting ATP balance, glucose regulation, repair signaling, and sleep can push the system further into dysfunction